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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 03
Predictors of In-Stent Restenosis after Coronary Angioplasty
Ibtissam Romani, Safia Soukrat, Laila Bendriss
Published: March 30, 2019 | 62 47
DOI: 10.36347/sjams.2019.v07i03.058
Pages: 1156-1165
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Abstract
Background: Stents represent a major improvement for the coronary revascularization. However, restenosis (ISR) remains an important complication as it limits its effectiveness and may require new therapeutic interventions. The aim of our study is to define the predictive factors of this phenomenon. Material and methods: It is a retrospective study of 83 patients admitted in the cardiology department of the Military Hospital Avicenna in Marrakech during 2 years, who underwent coronary angioplasty and stenting. We have compared two groups of patients: 18 with restenosis (ISR+) and 65 without restenosis (ISR-). Results: The prevalence of ISR is 21.1%. The mean age is 59, 10 years. The population of ISR is characterized by high rate of diabetes (p: 0, 0001), the cumulation of more than 3 coronary risk factors (p: 0,0027). Stenting have interested the left anterior descending artery (LAD) in 52.2% of cases among the group with restenosis (p: 0, 0008).The stented lesions in RIS+ group are complex (p: 0,03) and lengthy (p : 0,04). Long stents were the most implanted (p: 0,0001). According to literature data, the independent predictive factors of restenosis in our study are diabetes (OR = 0.011), cumulative cardiovascular risk factors (OR = 0.027), lesions on the proximal LAD (OR = 0.03) and the use of long stents (OR = 0.01). Conclusion: At the end of our study, we can identify a group of high-risk patients who actually benefit from the use of active stents, which currently reduce the occurrence of restenosis.