DOI: 10.36347/sjams.2019.v07i03.071

Pages: 1230-1233

Prediabetes is a condition that involves impaired glucose tolerance or impaired fasting glucose. Studies have shown that people with prediabetes tend to develop type 2 diabetes over a period and are at increased risk for cardiovascular disease and death even before the development of diabetes. Early detection of prediabetes status becomes more important when first-degree relatives of patients with Type 2 diabetes are concerned as genetics is an unmodifiable risk factor. The objective of our study was to determine the prevalence of prediabetes in first-degree relatives of patients with Type 2 diabetes mellitus in a rural population of south India.100 first-degree relatives of patients with Type 2 diabetes mellitus were included in this study. Study protocol included detailed clinical history, examination and investigations. Blood samples for fasting blood sugar and 2 h post glucose blood sugar were taken. In the present study of a total of 18 subjects had prediabetes based on their FBS levels and 12% of the individuals had newly detected diabetes mellitus by this method. In this study impaired glucose tolerance was present in 20% of the study population and14% of the individuals had newly detected diabetes mellitus by this method. Prevalence of prediabetes is increasing in rural sectors of our nation. Early detection of prediabetes in a susceptible group is important. Lifestyle modifications (dietary restriction and exercise) and certain medications can prevent the development of diabetes in persons with prediabetes. More prospective studies with a larger population are needed.