DOI: 10.36347/sjams.2019.v07i03.077

Pages: 1252-1255

Introduction: High blood pressure (BP) is a major public health problem in India and its prevalence is rapidly increasing among both urban and rural populations. In fact, hypertension is the most prevalent chronic disease in India. The prevalence of hypertension ranges from 20-40% in urban adults and 12-17% among rural adults. Studies elsewhere have revealed association of microalbuminuria with early myocardial dysfunction in the form of left ventricular diastolic dysfunction. Objective: To study association of microalbuminuria with early myocardial dysfunction in the form of left ventricular diastolic dysfunction in patients of newly diagnosed, untreated and uncomplicated essential hypertension. Method: A prospective, stratified randomized, observational study was conducted on two hundred patients of newly diagnosed, untreated and uncomplicated essential hypertension who visited the medial outpatient department of Patna Medical College and Hospital between January 2014 and December 2014. The patients were subjected to a battery of test for imaging the heart and that included a standard chest roentgenogram, 12 lead ECG, Echocardiography, routine urine test and test for microalbuminuria. The results were statistically analyzed. Result: Positive co relation was observed in patients with newly diagnosed, uncomplicated, untreated hypertension having microalbuminuria with Left Ventricular Diastolic Dysfunction diagnosed by echocardiography. Conclusion: In the study microalbuminuria was found to be directly related with preclinical impairment of LV diastolic function and thus it can be used as early and reliable marker of preclinical cardiac structural and functional dysfunction.