DOI: 10.36347/sjams.2019.v07i03.090

Pages: 1309-1311

The antiphospholipid syndrome is characterized by the combination of antiphospholipid antibodies and arterial and / or venous thrombotic phenomena. Ocular vascular involvement is described in the literature and may be indicative of the syndrome. His diagnosis is all the more important as the ocular and even vital prognosis of these often young patients can be engaged. We report an observation illustrating this situation. A young people aged 32 presented with a sudden unilateral loss of vision. Fundus examination and fluorescein angiography revealed a severe retinal vascular occlusion. an antiphospholipid syndrome was discovered during etiological check-up. It was associated with a heterozygot state mutation of Leiden V factor. In most cases central artery or vein occlusion means atherosclerosis. However, other etiologies must be studied in young patients. According to several studies: antiphospholipid syndrome has been detected in 5% to 33% of the patients showing a major vascular retinal obstruction. The association of thrombophilia must be considered because it increases the risk of thrombotic recurrence. The antiphospholipid syndrome must be studied in cases of numerous and severe retinal vascular obstruction occurring in young patients, even if vascular risks exist. This diagnosis is important because it may imply a long-lasting anticoagulative or an antiaggregative treatment to significantly reduce the risk of recurrent thrombotic events.