DOI: 10.36347/sjams.2019.v07i01.009

Pages: 55-60

Introduction: Gestational diabetes mellitus (GDM) is a metabolic disorder defined as glucose intolerance with the onset or first recognition during pregnancy. Women with GDM are at increased risk for adverse obstetric and perinatal outcome. This study was done to determine the frequency of insulin resistance in GDM/IGT pregnant women during antenatal population. Materials & Methods: Patients meeting the inclusion criteria underwent fasting serum insulin and fasting plasma glucose measurements. HOMA calculator (software based) was used to calculate the HOMA-2IR value, which was taken as a measure of insulin resistance. Based on the inclusion criteria, 60 patients were followed up though their antenatal and period, and obstetric outcome measures were documented. Prevalence of insulin resistance was calculated using HOMA-2IR value of more than 1.9 as cut off. Total patients screened and delivered at a tertiary care teaching hospital, Haldia, West Bengal during the period of study were taken as the denominator. Results: Majority of pregnant women belongs to 18-30 yrs age group (56.12%), followed by 32.09% and 11.80% in 31-40 and above 40 yrs age group. Present study revealed the prevalence of impaired glucose tolerance and GDM in patients delivering at our hospital over a period of 6 months (Jan-June 2016) was 9.31% and 3.11% respectively. The total number of patients with HOMA-2IR>1.9 was found to be 8 (8 out of 100.) The prevalence of insulin resistance is 8% amongst the antenatal patients in the study. Prevalence of Cesarean delivery and assisted vaginal delivery was higher in in study group 13.33% and 31.7% respectively. The percent prevalence of shoulder dystocia (5%) and postpartum hemorrhage (PPH) (25%) were also higher in GDM/IGT patients.