DOI: 10.36347/sjams.2019.v07i02.032

Pages: 589-591

Background: Thyroid hormones T3 and T4 play a very important role in regulating metabolism, development, protein synthesis and also influence other hormone functions. These hormones also tend to have a significant impact on Chronic Kidney Disease. CKD also affects the pituitary thyroid axis. Low T3 levels is one of the most common finding along with subclinical hypothyroidism in CKD patients. Methods: This prospective study recruited 105 consecutive patients with Chronic Kidney Disease presenting to medicine OPD in our institute over a period of 6 months. For all these patients FT3,FT4 and TSH levels were measured. Results: Out of 105 CKD patients 38 patients had low FT3 levels and 35 had low FT4 levels. 31 patients were found to have either Subclinical Hypothyroidism or Hypothyroidism. Conclusion: In this study we observed a high prevalence of Subclinical Hypothyroidism in CKD patients. Subclincal Hypothyroidism is a relatively common condition in CKD patients. The prevalence of hypothyroidism increased with the increasing severity of CKD.