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Scholars Journal of Applied Medical Sciences | Volume-7 | Issue 02
Serum Cystatin C – A Better Marker of Preeclampsia
Dr. U.N. Priyadharshini, Dr. B. Shameem
Published: Feb. 28, 2019 | 229 117
DOI: 10.36347/sjams.2019.v07i02.052
Pages: 690-692
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Abstract
The purpose of this study was to determine whether the levels of cystatin c are significantly elevated in women diagnosed to have preeclampsia. We performed a case control study to compare the levels of cystatin c in women with preeclampsia (n=40) and normotensive antenatal women (n=40). Uric acid and creatinine levels were also compared. Serum Cystatin C estimation was done by nephelometry and the mean value was significantly higher in women with preeclampsia when compared to normal pregnancy (1.12±0.06mg/L and 0.69±0.03mg/L respectively). Uric acid levels were also significantly elevated in cases when compared to controls but there was no significant correlation between cystatin C and uric acid levels in cases (6.54±0.27mg/dl and 3.92±0.15mg/dl respectively). Creatinine levels were not elevated both in cases and controls (0.76±0.05mg/dl and 0.67±0.02 mg/dl respectively).