DOI: 10.36347/sjams.2019.v07i02.070

Pages: 763-765

Essential Hypertension though being one of the major global health burden, its pathophysiology is still not established well. This is because it is a complex disorder with multiple factors contributing to its evolution. Recently, hormones like Leptin secreted by adipose tissue are gaining significance in research studies linking hypertension and obesity. So we decided to find the association of serum leptin levels with essential hypertension and whether it is independent of obesity. The study included 60 essential hypertensives in the age group of 45-60years with both genders. Anthropometric measurements and blood pressure were recorded. Body mass index were calculated. Serum leptin levels were measured from collected fasting blood sample. Descriptive statistics were derived. Binary logistic regression was done. Serum leptin levels were found to be increased in hypertensives even after adjusting for obesity with p value<0.000