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Scholars Academic Journal of Biosciences | Volume-3 | Issue-05
Sensitivity profile of microorganisms causing urinary tract infection in humans in the city of Lavras, Minas Gerais, Brazil
Paula Novato Gondim, Stela Márcia Pereira, Luciano José Pereira, Eric Francelino Andrade, Ticiana Meireles Sousa, Joziana Muniz De Paiva Barçante, Márcio Gilberto Zangeronimo
Published: May 30, 2015 | 202 107
DOI: 10.36347/sajb.2015.v03i05.007
Pages: 456-463
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Abstract
Urinary tract infections (UTIs) have high prevalence and incidence. We evaluate the profile of microorganisms that cause UTIs in patients seenPublic Laboratory of Lavras, Minas Gerais, Brazil, from January, 2011 to May, 2012. Besides, we evaluate possible cyclical variations and tendencies, as well as sensitivity of the microorganisms to different antibiotics. It was used secondary data from the “Sonner” Computer System that’s assistsof the Brazilian Public Health System - SUS (DATASUS – SUS “Sistema Único de Saúde”). Two thousand one hundred thirty-five routine urinalysis, followed by urine culture and antibiogram, were analyzed, with 483 positive results. Most of the samples were from women (88%). The majority of patients had 60 years old or older. Gram-negative bacteria found were Escherichia coli, Proteus sp, Klebsiella sp, Enterobacter sp and Pseudomonas sp, where as gram-positive Staphylococcus sp and Streptococcus sp. E. colishowed the highest prevalence (77.3%). Antibiotics that showed greater efficacy against gram-negative bacteria were amikacin and ceftriaxone, and these microorganisms were more resistant totrimethoprim/sufametoxazol. Gram-positive bacteria showed sensitivity to chloramphenicol and rifampicin and greater resistance tooxacillin. It could be observed that most of the urine samples submitted to culture were negative for UTIs. The prevalence of microorganisms causing UTIs can vary among different locations, thusit is important to know the local scenario and maybe change empirical treatment according to each region.