DOI: 10.36347/sajb.2015.v03i08.001

Pages: 640-643

Epidermal growth factor (EGF) is used widely in management of diabetic foot wounds to augment wound healing and to promote epithelialization. There are reports of its use in management of oral mucositis in patients receiving head and neck radio therapy. However reports of its use in management of diabetic oral ulcers are rare. we present here a case of non healing diabetic oral ulcer which we managed using tropical EGF. A 45 year old patient who is suffering from diabetes presented with non healing ulcer of oral cavity. Based on reports of investigations the ulcer was diagnosed as non healing major aphthous ulcer. oral hypoglycemic and insulin therapy was started to manage hyperglycemia. Normal glycemic control was achieved in 5 days and tropical EGF and antiseptics were given to augment ulcer healing. Healing started on 8th day and progressed to complete healing by 21st day. Tropical epidermal growth factor can be used effectively in management of non healing diabetic ulcers of oral cavity.