DOI: 10.36347/sajb.2015.v03i09.001

Pages: 725-732

The powder commonly called SPIRULINA is made of Spirulina platensis, a microalgae cultivated for centuries and used in a preventive and curative purposes. Studies conducted on this blue-green algae cultivated in some countries of the world have shown many nutritional and pharmacological properties. This is what justifies its use in all the continents as nutritional supplement. With the scarcity of works done on SPIRULINA produced in Côte d'Ivoire, we set ourselves the objective to evaluate the anti-anaemic activity of this algae in the rabbits of Oryctolagus cuniculus species.In this studies we evaluated the anti-anaemic effect by administering SPIRULINA by oral route at different doses to different groups of phenylhydrazine hydrochloride anaemia rabbits(Oryctolagus cuniculus) and compared its effect with a reference antianaemic (Ranferon®-12). Hemograms by days: 2, 5, 12 and 19 showed a very highly significant increase in red blood cell count, hemoglobin and hematocrit at used doses. However, these increases were greater in treated groups at doses of 2000 mg / kg-bw and 4000 mg / kg-bw. Therefore, increases of 153.53% and 124% were observed respectively for red blood cell count and hematocrit at 2000 mg / kg-bw. For the dose of 4000 mg / kg-bw, we noticed an increase of hemoglobin at a rate of 77.74%. However, no significant difference was obtained between haematological parameters of treated groups of animals by both SPIRULINA and Ranferon®-12 at the end of treatments.To sum up, our study showed that SPIRULINA has an anti-anaemic effect in rabbits.