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Scholars Academic Journal of Pharmacy | Volume-3 | Issue-02
Choice of Drug Eluting Stent: A Review
Jasmine George, Hari. A, Lincy George, L. Panayappan, K. Krishnakumar
Published: Feb. 28, 2014 |
316
162
DOI: 10.36347/sajp
Pages: 150-152
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Abstract
The development of stent has been a major achievement in treating obstructive coronary artery disease
(OCAD). The main obstacle in the long term success of percutaneous coronary intervention (PCI) was the neo-intimal
hyperplasia developed within the stent, which may leads to instent restenosis. The introduction of Drug-eluting stents
(DES) shows steep decrease in angiographic restenosis when compared with bare metal stent. The ability of DES to
prevent the restenosis after balloon angioplasty reduces the complications associated with sub acute stent thrombosis and
late stent restenosis by decreasing the incidence of MI. The coating of bioabsorbable polymers on DES enhances
antiproliferative drug release. This review article reveals various types of drug eluting stents and their comparison with
bare metal stents