DOI: 10.36347/sjams.2016.v04i07.021

Pages: 2405-2407

Primary mucinous adenocarcinoma (PMC) of skin is a rare adnexal epithelial neoplasm with eccrine differentiation. It is a rare tumour most commonly affecting the face and scalp region. We should be cautious before making its diagnoses as it closely mimics metastatic mucinous carcinoma from internal organs and a thorough search for any primary is warranted. Diagnosis can be only confirmed after excluding a primary mucinous carcinoma of other organs like breast, gastrointestinal tract, lung, salivary and lacrimal glands, urinary tract, prostate or paranasal sinuses metastatic to skin. Here, we report two cases of primary mucinous adenocarcinoma, one of axilla and other arising in periorbital region of face. Both the cases shows presence of PAS positive, diastase resistant mucin and are negative for CK-20 expression. Patients were undergone through an extensive search for any other neoplastic lesion by doing CT scan of thorax and abomen, upper GI tract enoscopy, colonoscopy, USG lower abdomen and pelvis but reveals nothing. Both the patients are doing well on one year follow up period.