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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-08
A Study of Efficacy of Botulinum Toxin Type A in Treatment of Hyper salivation
Dr Arun Tyagi, Sanjay I Totlani
Published: Aug. 30, 2016 | 64 44
DOI: 10.36347/sjams.2016.v04i08.001
Pages: 2736-2738
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Abstract
Hyper salivation or drooling is unintentional loss of saliva from the mouth, seen usually in patients with neurological deficits such as cerebral palsy, motor neuron disease or Parkinson’s disease. Persistent drooling may cause problems in social development of patients, as well as problems related to personal hygiene. Many studies have investigated the clinical improvement in drooling after the injection of botulinum toxin type A (BTXA). Our present study was performed in cerebral palsy patients in whom we followed a simplified procedure of Injecting Botulinum toxin in children of cerebral palsy at lower doses than other study. USG studies were not carried out and injections were given based on anatomy and palpation of the gland which is superficial. Fourteen cerebral palsy patients (6-15 years-of-age; mean 08yrs, 08 boys and 06 girls) were injected with 0.5 units/kg body weight of Botulinum Toxin Type A in each parotid. Three injections with an insulin syringe were given in each parotid. Children were followed up weekly for first four weeks and thereafter monthly. Twelve children out of fourteen showed improvement following BTXA injections, thus demonstrating that Botulinum Toxin Type A injection is an effective treatment of hyper salivation.