DOI: 10.36347/sjams.2016.v04i08.011

Pages: 2783-2786

The objective of present study is an analysis of the clinical profile of malaria with emphasis on complicated malaria cases in the two major tertiary referral medical college hospitals in the endemic area of Vijayapur over a period of 7 years. A total 210 cases presenting with fever from November 2009 to January 2016 were included in this study. All patients above 18 years with fever and proved to be having acute malaria via peripheral smear study, QBC test or pLDH antigen test positive for malarial parasite were included in this study. A total of 210 cases were diagnosed with malaria. 123 were male and 87 female. Complicated malaria was seen in 53 cases. 3 died with the overall mortality of 3.7%, causative organism in all being P. Falciparum. Mortality occurred in those admitted with multiple organ dysfunction syndromes. Rest of the patients were treated with anti-malarial agents with recovery. Chloroquine was used in those initially suspected as clinical malaria, followed by quinine or Artemisinin in confirmed cases. .Supportive management of complications such as coma, convulsions, metabolic acidosis, hypoglycemia, fluid and electrolyte disturbances, renal failure, secondary infections, bleeding disorders and anemia was done. P. falciparum was predominant cause of most complications. P. vivax also caused severe malaria complications. However the occurrence of multiple complications leads to higher mortality in the P. falciparum group. Hence, early detection with effective treatment should be the aim to reduce mortality and morbidity associated with malaria.