DOI: 10.36347/sjams.2016.v04i08.042

Pages: 2943-2949

Abnormal Cold Pressor Response [CPT] is one of the important characteristic of autonomic dysfunction as well as future development of hypertension. Appropriate identification and intervention at early stages can prevent cardiovascular related morbidity and mortality. With this background we tried to identify if any abnormal response to Cold Pressor Test [CPT] in normal subjects. This test was carried on 60 healthy I MBBS 30 males and 30 females students aged between 19 – 25 years. Standard Mercury Sphygmomanometer was used to determine Blood pressure SBP and DBP. Heart Rates [HR] were recorded before and after the Cold Pressor Test [CPT]. The Cold Pressor Test [CPT] was performed following Hines–Brown’s method, with subjects immersing their left hand in 4°C water for 1 min and values were recorded in appropriate format. In males the Mean SBP was found to be 118.96 ± 5.86 and in females the values were 121.14 ± 7.0 before the start of the test. The mean values of SBP during CPT were 129.41 ± 6.04 for males and 135.5 ± 4.14 for females, the calculated p values were found to be < 0.05 and were found to be significant. The mean value of DBP in males before test were 83.86 ± 8.02 and females were 84.53 ± 6.51 The mean values of DBP during CPT in males 96.53 ± 8.58 and in female were 95.9 ± 7.29. Basal Heart Rate mean values in males were 79.95 ± 8.06 and for females it was 84.5 ± 6.75. Maximum Heart Rates recorded during application of Cold Pressor Test [CPT] for males were 110.05 ± 10.9 and for females it was 118.86 ± 15.5 the calculated p values were significant. In the present study it was found that the response to CPT by both male and female varies. Whereas the females showed significant increase in SBP and heart Rate as compared to male counterparts. We also found that there were more numbers of hyperreactors to CPT in male as compared to females.