DOI: 10.36347/sjams.2016.v04i08.048

Pages: 2976-2985

The intranasal delivery is preferable route for administration of the drug for local, systemic as well as central nervous system drug delivery. Advantages of nasal spray dosage form such as it is cost-effective, easy to use/carry and self-adminis¬trable, it has high patient compliance make this dosage form growing opportunity for nasal drug delivery. This article outlined the relevant aspects of nasal anatomy, physiology and histology, and the biological, physicochemical and pharmaceutical factors that must be considered during the formulation development of nasal spray. It is intuitively expected that this review will help to understand nasal formulation and it’s in- vitro characteristics.