DOI: 10.36347/sjams.2016.v04i08.061

Pages: 3048-3053

The present study was designed to evaluate the effects of hydroalcoholic extract of Nardostachys jatamansi on experimentally induced ulcer by pylorous Ligation method. The extract (500 mg/kg) was administered orally in rats 60 minutes before the induction of ulcer using pyloric ligation method. Volume of gastric secretion, pH of gastric juice, Free acidity, Total acidity, Ulcer index were calculated to examine ulcer preventive ratio of the extract. The extract of Nardostachys jatamansi (500 mg/kg) significantly inhibited ulcer formation in Pyloric ligation models. These findings justify the use of this Nardostachys jatamansi traditionally in the treatment of ulcer.