DOI: 10.36347/sjams.2016.v04i09.026

Pages: 3312-3313

S. aureus is by far the most important human pathogen among the staphylococci. S. aureus is one of the most common causes of healthcare and community associated infections. It has a remarkable capacity of acquiring different mechanism of resistance to various antibiotics. The main aim of this study is to establish the antimicrobial susceptibility pattern of S. aureus and to identify the degree of resistance to commonly used antibiotics so that empirical therapy can be modified accordingly. Total 150 isolates of S. aureus from various clinical specimens are included in the study. S. aureus isolates are identified by colony morphology and gram stain and confirmed by catalase and coagulase test. Antimicrobial susceptibility testing was done on Muller Hinton agar by Kirby-Bauer method using 17 different antibiotics. The study shows that S. aureus shows higher degree of resistance to penicillins and cephalosporins and more sensitive to aminoglycosides, fluoroquinolones,and macrolides. Co-trimoxazole and tetracycline are also a better options when there is resistance to other group of antibiotics. Vancomycin and teicoplanin shows 100% sensitivity.As drug resistance is so common among S. aureus, the appropriate antibiotic should be chosen based on antibiotic sensitivity testing.