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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-09
A study of Efficacy and Safety of Intravenous Iron sucrose for the treatment of Severe Anaemia in antenatal and postnatal women at community Health Center, Prantij, Gujarat, India
Ashutosh D Jogia, Bhavesh R Kanabar , Jinesh B Rathod
Published: Sept. 30, 2016 | 44 56
DOI: 10.36347/sjams.2016.v04i09.033
Pages: 3335-3339
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Abstract
Anaemia is a leading cause of maternal death in the world. In the world about 50% maternal deaths occur in south-east Asia and in south east asia, 80% maternal death occur in India due to anaemia. The traditional treatment of iron deficiency anaemia includes oral iron and blood transfusion. Both of these have their own drawback so now IV infusion of iron sucrose is first line for the therapy of moderate to severe anaemia. So this study is done with the objective to determine the iron sucrose efficacy and safety in treatment of iron deficiency anemia. This was a prospective study. Total 102 patient having Hemoglobin between 4-7 gm/dL were included in the study. Intravenous Iron sucrose was started as per national guideline. The study subjects were examined to record their haemoglobin level and asked about adverse effects after 3 dose (1 week) and 6 dose (2 week). Recorded data was entered in MS Excel 2016. Result published as percentage and mean. During the first two week almost 1.2 gm% increase in Hb level after every week (after 3 dose). Swelling at injection site was most common (8.8%) adverse effect observed in 1st dose as well as in subsequent doses. Delayed hypersensitivity was reported in 3 cases in subsequent doses. As per this result conclude that Intravenous infusion of iron sucrose is very effective in iron deficiency anaemia. It increases Hb level at a faster rate than other known iron preparation.