DOI: 10.36347/sjams.2016.v04i09.055

Pages: 3440-3441

Hepatitis B virus is among common cause of transfusion transmitted disease. So it is necessary to diagnose HBsAg positivity before issuing blood to patient in blood bank. There are various methods for detection of HBsAg reactivity but our focus is to evaluate effectiveness of rapid diagnostic test kits as compared to ELISA methods at blood bank for screening of blood donors. This study was carried out at tertiary care hospital (blood bank), Gujrat , India from date of 01/01/2016 to 31/08/2016.We have tested total 10892 donor sample with using third generation ELISA kit as well as Rapid diagnostic kit. Rapid diagnostic kit showing sensitivity 87.5%, specificity 100 %, positive predictive value 100%, and negative predictive value 99.90%.Among all donor mean age group was 29 year and most of patients are male. Rapid diagnostic kits can be used in emergency situation as it is less time consuming and no specific training required but its sensitivity is less and gives false negative result in few donor so it cannot replace standard ELISA test.