DOI: 10.36347/sjams.2016.v04i10.019

Pages: 3640-3643

The aim of the present study was to analyze the etiological factors, clinical spectrum and outcome of pregnancy related acute kidney injury. A total of 64 women with pregnancy related acute kidney injury admitted in department of nephrology, Sri Aurobindo Medical College and Post Graduate Institute were recruited for the study. Data regarding age, parity, obstetrics complications encountered and clinical outcome of patients were recorded in predesigned proforma. Sepsis was the dominant cause of AKI in pregnancy and was present in 29(45.3%). Other causes includes APH/PPH (19%), preeclampsia/eclampsia (19%), HELLP (9.5%), HUS (3.1%) and malaria (3.1%). Anemia and thrombocytopenia was observed in 47(73%) and 7 (10.9%) cases respectively. Hypertension and tachycardia was observed in 19(39.7%) and 29(45.3%) cases respectively. Seven patients were succumbed to their illness. Of the 54(84.4%) surviving patients, 33(51.5%) had complete recovery of renal functions, 17(26.5%) had partial recovery and 7(10.9%) became hemodialysis dependent. Pregnancy related acute kidney injury is a life threatening condition. Prophylactic measure may be taken to avoid sepsis which is major etiological factor for PR-AKI.