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Scholars Journal of Applied Medical Sciences | Volume-4 | Issue-10
Association of high-grade prostatic intraepithelial neoplasia (HGPIN) in patients of prostate adenocarcinoma
Pragya Gautam Ghimire, Ashok Kumar Kapoor, Yamini Jindal, Sandeep Gupta
Published: Oct. 31, 2016 |
179
97
DOI: 10.36347/sjams.2016.v04i10.039
Pages: 3753-3757
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Abstract
Present study aims at assessment and histopathological examination of prostate tissues from 50 subjects having lower urinary tract obstruction. Forty of 50 subjects had benign prostatic hyperplasia (BPH) and other 10 subjects had adenocarcinoma prostate. Subjects with prostatic carcinoma were labeled as patients. Age of the patients ranged from 56 to 82 (median 70) years. All the patients were farmers. Nine of 10 patients consumed both red and white meat. Prostate carcinoma was graded according to Gleason’s criteria. Accordingly, 5 patients had Gleason score 9 or 10. Four patients had Gleason score 6 to 8. Another patient had Gleason score 4. Two of 10 patients also had prostatic intraepithelial neoplasia (PIN). Perineural invasion (PNI) was seen in 2 patients. One patient also had vascular invasion. PIN appeared to be associated with prostatic adenocarcinoma in 2 patients and may have the role in prognosis of prostatic adenocarcinoma.