An International Publisher for Academic and Scientific Journals
Author Login
Scholars Academic Journal of Pharmacy | Volume-3 | Issue-05
Biological Analysis and Phytochemical Studies of The Exocarp Fruits Extracts of African Star Apple (Chrysophyllum albidum G. Don)
Orijajogun O. Joyce, Olajide O. Olutayo and Useh U. Mercy
Published: May 30, 2014 |
236
263
DOI: 10.36347/sajp
Pages: 379-382
Downloads
Abstract
The exocarp of the fruit extracts of Chrysophyllum albidum was extracted using hexane and ethyl acetate. This
study was carried out to investigate the phytochemicals and to also test for antimicrobial activity. These extracts were
tested against some gram-negative organisms (Escherichia coli, Klebsiella pneumonia) and gram-positive organism
(Staphylococcus aureus) using disc diffusion and micro broth dilution techniques with the disc concentration 60 µg/disc.
The entire organisms were sensitive to ethyl acetate extract of the plate at 30 µg/disc concentration as follows; E. coli (9
mm), Klebsiella spp. (9 mm) and Staphylococcus spp. (11 mm). E.coli and Staphylococcus spp. were insensitive in the
hexane extract and they were not inhibited. Except Klebsiella spp. that is sensitive at a disc concentration of 60 µg/disc
with zone of inhibition diameter of 9mm.The result of phytochemical studies of both extracts show the presence of
alkaloids, saponins, steroids, tannins and volatile oil but saponins and tannins are absent in the hexane extract.