DOI: 10.36347/sjams.2016.v04i12.019

Pages: 4272-4278

Relationship of Echocardiographic findings with hypertension and biochemical parameters in Chronic Kidney disease (CKD) patients has not been clarified. We aim to correlate the echocardiographic findings with different biochemical parameters in chronic renal failure patients. In this study we included 50 cases of CKD and 30 controls. Detailed history, clinical examination and relevant investigations with 2D and Colour Doppler Echocardiography were conducted in all cases and control. We found that CKD patients have highly increased incidence of pericardial effusion, left ventricular hypertrophy (LVH), diastolic dysfunction, valvular regurgitation and left ventricular dilatation. Diastolic dysfunction significantly correlated with blood urea levels, serum creatinine levels and decrease in hemoglobin levels. LV dilatation correlated with decrease in Hemoglobin levels. LVH was related to the presence of hypertension in CKD cases while diastolic dysfunction was not found to correlate with hypertension or LVH, which indicated that many other factors were responsible in causing diastolic dysfunction. Thus, timely identification and treatment of these cardiovascular abnormalities could alter the course of the disease and help in reducing morbidity and mortality of CKD patients.