DOI: 10.36347/sjams.2016.v04i12.026

Pages: 4311-4317

Human hepatitis E virus (HEV) was first reported in 1980 and is now considered a major cause of acute non-A, non-B hepatitis in humans. HEV infection is reported throughout the world and occurs in epidemic form in developing countries where the disease is endemic and is often associated with water contamination after heavy rains or flooding. Sporadic human HEV infections occur in industrialized countries where infected individuals contract the infection while traveling to endemic regions. It is important to have clear data about the prevalence rate of HEV in a country in order to facilitate the possible introduction of large scale national surveillance program and delivery of vaccination in the future and in consequence prevent the maternal and congenital mortality. This hospital based descriptive study was conducted in pregnant women for analysis of antenatal case for hepatitis E virus antenatal cases who attended the medicine department in Raja muthaiah medical college and Hospital, Chidambaram, during the period August 2015 till August 2016. Extensive data suggest that hepatitis E is a major contributor to disease and mortality across much of the Indian continent, with country-level variability, as expected. Still, it is challenging to make comparisons across these populations, given differing methodologies and assays used to determine HEV etiology. There was also lack of molecular techniques (HEV RNA detection) for confirmation of our results. All of the risk factors for the acquisition of HEV infection we’re not be addressed in the questioner.