DOI: 10.36347/sjams.2016.v04i12.029

Pages: 4325-4327

This study was designed to assess serum vitamin D status (25-OHD) in the reflux nephropathy patients and to compare it with a no reflux nephropathy control group. It also aimed to investigate the correlation of serum vitamin D level with vesicoureteral reflux severity and invalidation experiences. A total of 230 consecutive patients with RN and 240 Non RN control participants were enrolled. Venous blood samples were drawn from all participants to evaluate serum 25-OHD levels. Mann-Whitney tests and multiple logistic regression analyses were performed and Spearman's correlations were calculated. 470 children were examined (230 RN and 240 NRN). The deficiency(<10ng/ml )36 % in RN and 2% NRN( p-value 0.0001), insufficiency(10-30ng/ml)43% in RN and 5% in NRN (p-value=0.0003) , sufficient(30-150ng/ml)21% in RN and 93% in NRN(p-value=0.002) and potential intoxication (>150ng/ml) 0% in two group of vitamin D were observed in analyzed children with RN . There were no significant differences in serum calcium, phosphorus and gender. This study showed that although high rates of vitamin D insufficiency or deficiency were seen among RN patients and NRN participants, Addressing of invalidation experience especially by the patient's spouse is important in management of RN.