DOI: 10.36347/sajp

Pages: 444-448

Uraria lagopoides (L.) (Papilionaceae), a trailing perennial herb locally known as ‘Prisniparni’ finds use as a remedy for several ailments. The purpose of the present study was to evaluate scientifically the anti-diarrhoeal effects of Uraria lagopoides used traditionally in Indian system of medicine using castor oil-induced diarrhoea and castor oilinduced enteropooling in rats. The phytochemical studies of the ethanolic extract revealed the presence of flavonoids, glycosides, proteins and phytosterols. The extract showed significant (p< 0.001) protection against castor oil-induced diarrhoea and castor oil-induced enteropooling at (400 mg/kg). The plant extracts exhibited dose dependent antidiarrhoeal effects in the all treated groups and the results were compared with that of loperamide (3mg/kg, p.o) as reference standard drug.