DOI: 10.36347/sjams.2017.v05i05.015

Pages: 1789-1793

Intrahepatic cholestasis of pregnancy (ICP) is a condition in which serum bile acids are raised and it is associated with adverse fetal outcome. This is associated with severe pruritus with or without jaundice that resolves completely within 48 hrs following delivery and has a high recurrence rate in subsequent pregnancies. The prevalence of the condition varies worldwide from 0.2% in France to 2% in Scandinavia. The cause of obstetrical cholestasis is unknown. The study was undertaken to evaluate the correlation between maternal serum bile acid & feto-maternal outcome in intrahepatic cholestasis of pregnancy in Indian population. This was a prospective study done in tertiary care hospital over one year. Detailed history, investigations, feto-maternal outcomes were recorded and analysed. To conclude women with intra hepatic cholestasis of pregnancy is associated with increase adverse fetomaternal outcomes.