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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-05
Prevalence of Cryptosporidium in immunocompetent patients at a tertiary care centre at Moradabad, Western Uttar Pradesh, India: A One-year observational study
Yogendra Pratap Mathuria, Archana Singh
Published: May 31, 2017 | 53 65
DOI: 10.36347/sjams.2017.v05i05.048
Pages: 1953-1958
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Abstract
Cryptosporidiosis is a serious public health problem in most of the regions of the world, especially in developing countries, and represents a major cause of morbidity in children and among high-risk groups. The aim of the study was to find out the prevalence of Cryptosporidium infections in Moradabad district in immunocompetent patients in Western Uttar Pradesh and compare and correlate it with gender, age group, area (rural or urban) and main complains. Stool samples from 643 immunocompetent patients were collected and subjected to routine stool investigations during the study, i.e. Macroscopic examination was carried out for the presence adult worms or their body segments and microscopic examination such as stool wet mounts (both saline and iodine mounts), Modified Acid fast staining and ELISA for Cryptosporidium antigens were done. Out of total 643 patients, 178 (27.68%) had Cryptosporidium infection. Maximum numbers of patients were in the age group of 0-10yrs (277,43.08%) whereas out of these, 77 patients were found positive(27.8%), followed by 11-20 yrs age group(153,23.79%), and out of these, 53 (34.64%) were found positive, thus total positive patients of or less than twenty years of age were130,(73.03% of all positive patients).Out of total 643 patients, 383 (59.57%) were male and 260 (40.43%) were female patients and out of total 178 positive patients,105 (58.98%) were male patients. Most of the positive patients were from rural area, 108(60.67%). Diarrhoea(off and on) was the main complain in 163(91.57%) patients, followed by abdominal cramps in158(88.76%), anorexia and nausia in 101(56.74%) and Fever in 72 (40.44%) patients. Prevalence of Cryptosporidium infectionis high(27.68%)in Moradabad district in Western Uttar Pradesh.