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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-04
Clinical Outcome of Preterm Neonates with Thrombocytopenia
Bhagwan S. Natani , Pardeep Goyal , Ankit Agarwal, Namarata Saini, Sumit Bhatia
Published: April 25, 2017 |
232
119
DOI: 10.36347/sjams.2017.v05i04.042
Pages: 1430-1434
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Abstract
Thrombocytopenia is a common problem in preterm neonates. Thrombocytopenic neonates are at an increased risk of life threating complications. Hence this study was done with the objective to prospectively analyse clinical outcome of preterm neonates with thrombocytopenia. This prospective study was conducted in Department of Paediatrics, National Institute of Medical Sciences & Research, Jaipur. All intramural, singleton preterm neonates were included in the study. Enrolled neonates were screened for platelet count between 12-24 hour of life and later at 72 hour of life. Platelet count was repeated daily in thrombocytopenic infant. Neonates were followed till discharge. Statistical analysis was done using software SPSS version 23. 168 preterm babies gave the consent for inclusion in the study. 56 (33.3%) neonates had thrombocytopenia. 35 (20.8%) neonates had early onset of thrombocytopenia and 21 (12.5%) had late onset. 24 (42.8%) had mild, 20 (35.7%) had moderate and 12 (21.4%) had severe thrombocytopenia. Thrombocytopenic preterm neonates were diagnoses with sepsis, DIC, NEC and IVH. Severity of thrombocytopenia determined prognosis with severe thrombocytopenia having the highest mortality rate.