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Scholars Journal of Applied Medical Sciences | Volume-5 | Issue-04
Role of Antibiotic Prophylaxis in Laparoscopic Cholecystectomy-A Randomized Prospective Study
Rahul Sharma, R. K. Kajla, Dharmveer Jajra, Mohanlal, Diwan Jakhar
Published: April 25, 2017 | 213 94
DOI: 10.36347/sjams.2017.v05i04.081
Pages: 1652-1655
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Abstract
Surgical site infection is a rare complication during laparoscopic cholecystectomy, so role of prophylactic antibiotic is questionable. This was a hospital based prospective, randomized study comparing the prophylactic use of antibiotic ceftriaxone (Group A) vs placebo (Group B) in patients undergoing laparoscopic cholecystectomy. This study was conducted in department of general surgery, S. P. Medical College, Bikaner, and Rajasthan for a total duration of more than 1 year (Nov. 2015- Feb. 2017). During this study period, 200 patients were randomly divided in two groups. Overall, 2.07 % (4/193) cases were observed to have post laparoscopic cholecystectomy wound infection. Wound infection was observed in 1.04% (1/96) cases in group A and 3.09% (3/97) cases in group B (P> 0.05). In group A, 39.58% (38/96) cases and in group B 45.46 % (44/97) cases had fever post-operatively (p>0.05). Based on our study we concluded that for post laparoscopic cholecystectomy surgical site infection rate is very low (2.07%) and use of prophylactic antibiotics does not decreases the incidence of surgical site infection.