DOI: 10.36347/gamj.2023.v04i01.001

Pages: 1-5

Papillary thyroid carcinoma (PTC) is the most common type of thyroid malignancy, constituting more than 80% of thyroid cancers. Patients with PTC usually have excellent outcomes with appropriate therapy, while up to 30% of patients present with aggressive disease, including patients with locoregional recurrence and distant metastasis. Aim: The aim of this study is to analyze the characteristics of patients with papillary carcinoma of the thyroid with locoregional and distant recurrences. Materials and methods: Our study was retrospective and included 12 patients with locoregional and distant recurrences of papillary thyroid carcinoma, followed in the Day-Hospital unit of the endocrinology, diabetology, metabolic diseases and nutrition department of the Mohammed VI University Hospital of Marrakech. Résults: We included 12 cases of locoregional and distant recurrence of papillary thyroid carcinoma. 10 of our patients are female and 2 are male with a sex ratio of 1/5.The mean age of our patients was 47 years [22 - 69], 8 patients were younger than 55 years, and 4 were older than 55 years, the majority of our female patients are younger than 55 years. The initial surgical treatment consisted of lobo-isthmectomy in one patient, total thyroidectomy in 9 of our patients and thyroidectomy with lymph node dissection in 2 cases. Five of our patients had a tumor size greater than 4cm, in 3 cases the tumor size was between 2.1cm and 4cm, and in 4 patients it was less than 2cm. In our series we noted multifocality in only one patient. Capsular invasion was observed in 6 patients, representing half of the cases. As for the aggressive histological type, we noted only one case of a patient with the oncocytic variant of papillary carcinoma on anatomical-pathological study. Two of our patients had lymph node metastasis in the cervical region at the time of diagnosis. None of our patients had distant metastasis at the time of diagnosis. In one case the ATA risk stratification of ...