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Scholars Journal of Medical Case Reports | Volume-11 | Issue-01
The Bronchodilator Test on FEF 25%-75% in 34 Children and Adolescents with Asthma Sensitized and Non-Sensitized to House Dust Mites
Davisson do Sacramento de Lucena Tavares, Cyro Teixeira da Silva Junior, Adriana Alvarez, Priscilla Filippo Alvim de Minas Santos, Patricia Siqueira Silva, Eduardo Vieira Ponte, Joeber Bernardo Soares
Published: Jan. 7, 2023 |
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DOI: 10.36347/sjmcr.2023.v11i01.006
Pages: 20-22
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Abstract
The aim of this case series report was to assess the bronchodilator response on forced expiratory flow at 25%–75% of the vital capacity of children and adolescents with asthma, sensitized and non-sensitized to house dust mites (HDM). A retrospective study was evaluated in the Hospital Municipal Jesus, Rio de Janeiro, Brazil, with 34 participants enrolled as asthma sensitized (n=26) and non-sensitized (n=8) to HDM. In spirometry tests had not obstructions in large airways. Only the FEF 25%-75% values were found reduced in relation to the reference ranges (62% vs. 38%, X2=1.39, P=0.2383) for HDM and non-HDM, respectively. The bronchodilator test with salbutamol was statistically significant in both groups (P<0.005). The measure of bronchodilator response from FEF 25%-75% values was important to evaluate the reversibility of the small airways in children and adolescents with asthma who were sensitized and non-sensitized to HDM.