DOI: 10.36347/sjams.2019.v07i12.067

Pages: 4168-4173

Background: The renal system consists of the kidney, ureters, and the urethra. The overall function of the system filters approximately 200 liters of fluid a day from renal blood flow which allows for toxins, metabolic waste products, and excess ion to be excreted while keeping essential substances in the blood. Kidney is the one of the vital organs affected in cases burns, poisoning and trauma. Objective: Gross and microscopic changes in kidney of burns, poisoning and trauma case deaths; relation of renal changes with survival period and renal damage influencing fatal outcome. Materials and Methods: A prospective descriptive study at Government General Hospital Mortuary, Kakinada, Andhra Pradesh from September 2009 to October 2011 (2 year period). Cases of Burns, Poisoning And Trauma death autopsies during the study period i.e. fifty (50) cases of which burns cases – 20, poisoning – 15 and trauma cases - 15. All cases of burns, poisoning and trauma deaths where histopathology samples are compatible were included in this study. Observations: Burns victims were predominantly women (85%). Age of burn victims ranged from 17-80 years. Age of trauma victims ranged from 10-78 years. Age of poison victims ranged from 20-50 years. The frequency of major histological changes of kidney in burns, poisoning and trauma cases are recorded. Medical Intervention Lag Period also analyzed. An attempt is made to note the progression of kidney damage with increasing survival period. Relation between survival period and kidney change in burns, poisoning and trauma studied. Acute Renal Failure is observed in Burns, Poisoning and Trauma cases. Acute tubular necrosis is found in all three types of cases. Renomegaly was found predominantly in burns cases. Conclusion: Acute Renal Failure (ARF) is observed in burns cases, poisoning cases and trauma cases. Acute Tubular Necrosis (ATN) is found to be the cause of acute renal failure. Most of the kidney damage is occurring during the first .....