DOI: 10.36347/sajp

Pages: 337-339

High level of serum uric acid is important in diagnosis, cancer risk, recurrence and medical management of breast carcinoma. Serum uric acid provides a primary defense against human cancer based upon its capacity to scavenge singlet oxygen and its capacity to inhibit lipid per oxidation. To estimate Level of Serum Uric acid and Bilirubin in Breast cancer patients. The study includes 50 patients of breast cancer of 20-70 year age group along with age and sex matched healthy control. Serum Uric acid and Bilirubin was estimated from all participant and obtained data were analysed statistically by calculating p-value. In results the mean uric acid level increases (8.6 +1.3) with S.D. in study population and found to be significant (p<0.050) when compared to healthy control group uric acid level (mean+S.D. = 4.9 + 1.6). Bilirubin level were found to be 0.93 + 1.4 (mean+S.D.) in breast carcinoma patients while in healthy it was 0.86 + 2.6 S.D.(mean+ S.D.) and showed insignificant correlation when compared with control group (p=0.86). in conclusion the increased uric acid level may be a diagnostic marker in breast carcinoma as well as it showed oxidative stress in breast carcinoma and role of uric acid as antioxidant. However bilirubin level within normal limits in both groups showed role of bilirubin insignificant in breast cancer