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SAS Journal of Medicine | Volume-3 | Issue-12
Study of Lactate Dehydrogenase in Patients with Acute Stroke
Dr. Sanjib Kumar Shah, Sunil Shah, Dr. Shishir Regmi, Dr. Rajeshwar Prasad Kothari
Published: Dec. 30, 2017 |
74
52
DOI: 10.21276/sasjm.2017.3.12.4
Pages: 333-334
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Abstract
Lactate Dehydrogenase (LDH), an enzyme found in living cells, is released
during the tissue damage. The study was planned to study the level of serum lactate
dehydrogenase and consciousness level in patients of stroke. Level of serum lactate
dehydrogenase and consciousness level of 20 stroke patients were estimated and
correlated with the disease and its severity. Serum lactate dehydrogenase was
significantly elevated in 17(85%) of the patients. The Spearman correlation between
serum lactate dehydrogenase and stroke was significant (Spearman correlation=0.546,
p=0.019).However, the change in the serum lactate dehydrogenase was not related to
the severity of the disease as assessed by Glasgow coma scale. Lacate Dehydrogenase
is significantly increased in patients with stroke which may have beneficial role in
diagnosis and management of acute stroke.