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Scholars Academic Journal of Pharmacy | Volume-5 | Issue-01
Green Preparation of Jasmine Oil Mediated Bovine Serum Albumin Nanodiscs/nanocubes
Kirti Rani
Published: Jan. 30, 2016 |
210
103
DOI: 10.36347/sajp
Pages: 9-11
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Abstract
The preparations of various metal and polymeric nanoparticles were under scientific considerations these days
to get the controllable geometry of prepared nanostructures with the ease of their smallest size at nanoscale. Many
chemically modified nanoparticles such as nanosphere, nanodiscs, nanocubes, nanowires and nanorods are going to be
fabricated with many biocompatible and nontoxic biomaterials (carbon nanotubes, chitosan, albumin and
lipopolysaccharides and polysaccharides) or metals ions (gold, silver, iron and copper). These fabricated biomaterials and
tagged metal ions were found to improve the oxidative etching effect in nanostructures (nanodiscs/nanocubes) that play
very important role in manipulation of nanostructure geometry and their analysis. Bovine serum albumin was found to
report a biocompatible, easy biodegradable and cost effective matrix for preparing the nanoparticles due to its well
known exploitable characteristics e.g. biocompatibility, non-antigen city and non-toxicity. Hence, this study can provide
an potential approach of green synthesis to control the shape of biocompatible bovine serum albumin
nanodiscs/nanocubes by using jasmine oil as naturally occurring cheap and easily available emulsifier. Characterization
of prepared bovine serum albumin was performed by using Scanning Electron Microscopy (SEM) to observe the
prepared nanodiscs/nanocubes which had been going to be minimized to the expected size at nanoscale. So, this designed
method can be proved a cost effective and green method to prepare non-toxic and biocompatible bovine serum albumin
nanostructures to explore further their therapeutic applications being as nonviral gene or drug nanocages to carry out the
site specific targeted delivery.