DOI: 10.36347/sasjm.2023.v09i02.013

Pages: 144-147

Introduction: Gougerot-Sjögren’s syndrome (GSS) is a systemic autoimmune disease with malignant transformation to non-Hodgkin’s lymphoma (NHL) as its most formidable complication. There are few associations described in the literature with other solid tumours. We report 5 cases of SGS associated with solid tumours. Methodology: This was a retrospective, descriptive study conducted in the Rheumatology Department of the Aristide Le Dantec University Hospital in Dakar from January 2006 to December 2020. Results: Over the period we collected 5 cases. They were divided into 3 men and 2 women with a mean age of 73.4 years (51-83 years). The average diagnostic delay was 158.4 months or 13 years (120-240 months). The tumour occurred during the evolution of the GSS in 3 cases while the GSS occurred during the evolution of the tumour in 2 cases. The associated tumours were prostate cancer in 3 cases, ovarian cancer in 2 cases and colon cancer in 1 case. Paraneoplastic hyperuricaemia was present in 2 patients. The evolution was marked by death in 2 patients. Conclusion: We report in our study 5 observations of SGS associated with solid tumors.