DOI: 10.36347/sajp

Pages: 240-244

The quality of a pharmaceutical product is directly related to the health of patients. This consideration is evidenced by the results of studies of various researchers, which show that a practical and precise method of analysis can be the first step in the rational use of medicines. Most of the time, drugs and medicines even with all its importance and all its uses lack analytical methods in the literature and in most official compendia for their Quality Control. During the development of a new analytical method, as liquid chromatography, must be considered various factors, such as reliability, detection and separation of all compounds of interest, speed analysis to optimize equipment and analysts, reduced need for pretreatment of the sample, low final cost analysis when the reagents, procedures and machinery are accounted, and use of non-toxic reagents neither for the operator or for the environment, that is, environmentally friendly methods. Using techniques, green methods considered, as infrared spectrophotometric and turbidimetric methods make remediation of environmental impacts frequently observed nowadays unnecessary. The use of simple and easy methods of execution, fast, precise, accurate and environmentally friendly becomes more and more interesting for the pharmaceutical industry in Quality Control of drugs and medicines. The lack of environmental friendly methods for the analysis of pharmaceuticals with minimum generation of toxic waste and the consciousness of the analytical decisions is a gap that currently drives the research groups.