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Scholars Academic Journal of Pharmacy | Volume-5 | Issue-09
Efficacy of dexamethasone in prevention of trismus in mandibular third molar surgery
Hamid Reza Mozaffari, Mohammad Ramezanian, Masoud Sadeghi, Roohollah Sharifi, Shabnam Sadeghilar
Published: Sept. 30, 2016 |
205
106
DOI: 10.21276/sajp.2016.5.9.4
Pages: 383-385
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Abstract
Corticosteroids (dexamethasone and methylprednisolone) have been reported to control postoperative outcome
when given preoperatively. The aim of study is to evaluate efficacy of dexamethasone in prevention of trismus in
mandibular third molar surgery. In a randomized double-blind and clinical trial study, 54 patients referred to Department
of Oral and Maxillofacial Surgery with age range of 18-26 years. In case group, 20mg oral dexamethasone 2 hours before
and 2 hours after surgery was used and in control group, 20mg multivitamin tablet 2 hours before and 2 hours after
surgery was used. How and maximum mouth opening were checked for every patients before surgery, 2 hours and 48
hours after surgery. The mouth opening size was statistically significant after 2 hours and 48 hours in case group
compared with control group that the mouth opening size was more in case group compared with control group. The
results showed that oral dexamethasone reduced trismus of third molar surgery and probably lower dose of
dexamethasone has faster efficacy on incisal opening after surgery