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    Scholars Academic Journal of Pharmacy | Volume-5 | Issue-10
        Potentiometric Determination of Cyclizine by PVC Membrane Sensor
        Seema Tomar
        
            Published:  Oct. 30, 2016 | 
             321
             213
        
        
        Pages:  392-398
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        Abstract
        The two ion-pair complex of Cyclizine (Cy) with sodium tetraphenyl borate (TPB) and Phosphotungstic acid
(PT) was prepared and used for the construction of Cy-selective electrode. The electrode based on the Cy-PT ion-pair
complex has a lower detection limit of 1.5 x 10-7 M in a linear concentration range of 3.5 x 10-7 – 1.0 x 10-2 M with a
slope of calibration curve of 50.5 mV/decay. The selectivity coefficient was calculated with separate solution method
dictates the high selectivity of the electrode over other tested ions.
    

