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Scholars Academic Journal of Pharmacy | Volume-5 | Issue-10
Potentiometric Determination of Cyclizine by PVC Membrane Sensor
Seema Tomar
Published: Oct. 30, 2016 | 220 125
DOI: 10.21276/sajp.2016.5.10.2
Pages: 392-398
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Abstract
The two ion-pair complex of Cyclizine (Cy) with sodium tetraphenyl borate (TPB) and Phosphotungstic acid (PT) was prepared and used for the construction of Cy-selective electrode. The electrode based on the Cy-PT ion-pair complex has a lower detection limit of 1.5 x 10-7 M in a linear concentration range of 3.5 x 10-7 – 1.0 x 10-2 M with a slope of calibration curve of 50.5 mV/decay. The selectivity coefficient was calculated with separate solution method dictates the high selectivity of the electrode over other tested ions.