DOI: 10.36347/sjmcr.2015.v03i09.033

Pages: 896-900

Epidermolysis bullosa (EB) is a rare, inherited group of disorders due to defects in the skin structures that clinically manifests with extensive, intractable and recurrent blistering of the skin, occurring either spontaneously or due to minor trauma or friction. There are three major types of EB, namely: simplex (EBS), junctional (JEB) and dystrophic (DEB), with a prevalence of 8.22 per 1 million births [1, 2]. A fifty day old male child was bought with complaints of fever since 4 days and recurrent blisters over the body since birth. The lesions were first noted at third day of life over the buttocks and right elbow, which initially appeared as blisters that ruptured in 2-3 days resulting in ulceration, the ulcers healed spontaneously with crusting, leaving behind a hypo pigmented scar. Born to second degree consanguineous parents, his older sibling also had multiple, similar lesions over the trunk and lower limbs, along with nail dystrophy. Skin biopsy for histopathological examination revealed presence of bullous cavities in the dermo epidermal junction without any inflammatory cells, thus confirming the diagnosis, the child was given supportive and symptomatic treatment with intravenous anti biotics, along with wound care. In conclusion we report cases of EB in a fifty day old male baby who presented with history of recurrent blisters and ulceration over the body since birth, born to a 2oconsanguineous parents, with history of similar complaints in the older, female sibling.