DOI: 10.36347/sjmcr.2015.v03i09.039

Pages: 919-921

Hairy cell leukemia (HCL) is a rare, indolent B-cell disorder. Opportunistic infections and second malignancy are common in patients with HCL. We report a 36-year-old man with HCL. The patient was treated with cladribine and achived to complete remission. He was admitted to the chest disease department with dispnea and fever after six month later of treatment of cladribine. Pleural effusion was detected at the right hemithroax in chest x-ray radiography. Cancer antigene 125 that evaluated due to exudative pleural effusion was detected high (845 U/ml).Tuberculosis pleurisy was determined in specimen of pleural biopsy. The patient received anti-tuberculosis treatment for six months and pleural effusion regresed. After three years, he complained from stomachache that medical treatment-resistant. Serum cancer antigene-125 level of the patient increased more (1245 U/ml). The diagnosis of adenocarcinoma revealed by specimens of endoscopic biopsy. Dosetaxel, cisplatine, dexametazone and 5-flouro-uracil was given to this patient for six cycles. The patient died because of pneumonia 6 months after this treatment.