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Scholars Journal of Medical Case Reports | Volume-3 | Issue-10
A case of Graves’ disease associated with Klinefelter’s syndrome
Hong LI , Yi-li LUO, Sharvan RAMPERSAD, Peng Yang, Chun-yan Li, Xiao-li Zhang, Chun-jun Sheng, Le Bu, Fei Yu, Shen Qu
Published: Oct. 30, 2015 |
149
179
DOI: 10.36347/sjmcr.2015.v03i10.017
Pages: 984-987
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Abstract
This is the first time a case of Graves’ disease associated with Klinefelter’s syndrome is being reported in a Chinese patient. We report the case of a 41- year male patient who was diagnosed as Graves’ disease with Klinefelter’s syndrome. The patient, a known 10-year history of hyperthyroidism, presented with an increase in the severity of his symptoms, which were hyperhidrosis, palpitations, and heat intolerance, together with the appearance of fine finger tremors, with some feminizing features such as feminine voice, absent laryngeal prominence and beard, smaller than normal testes. Chromosomal study (47, XXY) confirmed the diagnosis of Klinefelter’s syndrome.