DOI: 10.36347/sjams.2023.v11i03.009

Pages: 530-536

Introduction: In spite of modern medical advancement, there is some significant pregnancy loss during antepartum period. In majority of cases labour soon follows death of the foetus, but sometimes labour does not start for several weeks. So induction of labour is needed but the unfavourable cervix remains a well-recognized impediment to success of induction of labour in intrauterine foetal death. Prostaglandins in different Seems in different routes have been widely investigated to be used for induction of labour particularly when the cervix is unripe. Both Prostaglandin E1, and Prostaglandin E2 have been proved effective equally. Dinoprostone (PGE2), has been widely used for cervical ripening and labour induction. Misoprostol, a methyl ester of prostaglandin analogue, has been shown to be effective for cervical ripening and labour induction. Aim of the study: The aim of this study was to compare the effectiveness of vaginal misoprostol (PGE1 tablet) and prostaglandin (PGE2 gel) in order to induce labour among patients with intrauterine foetal death. Methods: This was a cross-sectional study and was conducted in the Department of Obstetrics and Gynaecology of Dhaka Medical College Hospital, Dhaka, Bangladesh during the period from July, 2004 to June, 2005. In our study we included 70 patients who were given and during labour induction. Our patients were equally divided into two groups – i) Group A (Patients were given Per- vaginal prostaglandin tablet) & ii) Group B (Patients were given Intra-cervical prostaglandin gel). Result: In total 70 patients from both the groups completed the study. In our study we found the mean age was 23.94±4.19 and 24.46±2.44 years in group A and group B respectively and the mean induction to onset of labour time was less in prostaglandin E2 group (5.97±3.75) hours, than in prostaglandin E1 group (8.24±3.19) hour but induction to delivery interval time was not significantly different in most of the patients in both groups. ..............