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Scholars Academic Journal of Pharmacy | Volume-6 | Issue-05
Expression of the nestin marker in the mucosa of human nasal inverted papillomas using immunohistochemical technique
Hatem Abdul khaleq Hatem
Published: May 29, 2017 |
216
140
DOI: 10.21276/sajp
Pages: 206-211
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Abstract
Inverted papilloma is a tumour which arising from the lateral wall of the nasal cavity. It is common in males in
4th to 6th decades and is fairly uncommon neoplasm of the nasal region. The epithelium of this tumour consist of many
layers, typically squamus or ciliated columnar cells. Sometimes transitional epithelium enclosed by layer of columnar or
squamous cells. A peroxidase-labeled streptavidin-biotin technique was used in Immunohistochemical staining. The
staining strength of epithelial cells in nasal papilloma mucosa was analogous to the nasal mucosa of inferior turbinate.
The staining was detained to the cytoplasm as well as the plasma membrane, which was deep in the basal part and feeble
in the upper part. Total removal of the tumour should be done as final management of inverted papillomas with very long
term follow-up ( nearly 2 years ) to notice any consequent recurrences