DOI: 10.36347/sjams.2018.v06i12.003

Pages: 4643-4646

To compare efficacy and safety of 50 microgram misoprostol vaginally with oral route for induction of labor at term gestation. Total 100 women with term gestation, with bishop score <= 4 with various indications for induction of labor were randomized. 50 cases were given 50microgram of misoprostol vaginally and another group 50 microgram misoprostol orally, four hourly (maximum 6 doses) or till the women went into active labor. Statistical analysis was done. It was found that in vaginal misoprostol group induction delivery interval was significantly less (10.2hr vs 16.45hr). Successful induction was significantly higher (90% vs 75%) than oral group within 24hrs of induction. As far as dose required is concerned in vaginal group 40.25% women needed only 2 doses for delivery in contrast to 35.25% in oral group with maximum 6 doses were required.