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Scholars Journal of Applied Medical Sciences | Volume-6 | Issue-12
Effect of Grey Zone Sample Testing of Transfusion Transmissible Infectious Diseases by Enzyme Linked Immunosorbent Assay in Blood Safety - Experience at a Tertiary Care Hospital Blood Bank from Western Odisha
Chitta Ranjan Prasad, Bijayalaxmi Sahoo
Published: Dec. 30, 2018 | 166 171
DOI: 10.36347/sjams.2018.v06i12.014
Pages: 4701-4703
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Abstract
Enzyme-linked immunosorbent assay is a standard protocol adopted in all blood bank centres in Odisha for screening blood units for transfusion transmissible infections (TTIs). But donors who are at the time of donation in window period, give ubiquitous readings and show results in grey zone. Repeat testing of these samples can help in reducing the risk of TTIs. This is especially cost effective in developing countries where nucleic acid amplification testing for TTIs has not been adopted universally.Till date most of the studies has been done regarding the utility of grey zone samples and its application in TTI screening procedures. So this study has been taken up to find out the utility of repeat testing for these grey zone samples and its role in enhancing the sensitivity of current Elisa technology used for blood donor screening.