DOI: 10.36347/sjams.2018.v06i12.024

Pages: 4749-4752

Tuberculosis disease is highly endemic in India. Main aim of the study is to know the impact of diabetes mellitus on clinical presentation and treatment outcome in patients with pulmonary tuberculosis. A case control study is done on 50 cases that are age and sex matched with 50 controls, visiting Government Chest Disease and TB hospital Warangal, on presumptive pulmonary tuberculosis patients, aged between 35-60 years. Thorough history, clinical examination Sputum for AFB, CBNAAT, Chest x-ray, CBP with ESR, RBS, FBS, PLBS, HBA1C are done on all patients. There is bidirectional association between tuberculosis and diabetes. Tuberculosis is more common in diabetes. There is no significant difference in clinical presentation between diabetics and non-diabetics with pulmonary tuberculosis. Clinical improvement at the end of treatment is good in non diabetics compared to diabetics. There is increased risk of active tuberculosis & high sputum positivity in cases with diabetes when compared to controls. There is also increased risk of relapse and poor outcome at the end of treatment in patients with diabetes.